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REPLICATION


While proposing the double helical structure for DNA, Watson and Crick had immediately proposed a schemefor replication of DNA. To quote their original statement that is as follows:‘‘It has not escaped our notice that the specificpairing we have postulated immediately suggests a possible copying mechanism for the genetic material’’(Watson and Crick, 1953). The scheme suggested that the two strands wouldseparate and act as a template for the synthesis of new complementary strands. After the completion of replication, each DNA molecule would have oneparental and one newly synthesised strand. Thisscheme was termed as
semiconservative DNA



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